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基于DPPH、ABTS自由基清除试验，铁离子还原能力（ferric ion reducing antioxidant power, FRAP）3种抗氧化模型研究麦角硫因分别与绿原酸、没食子酸、阿魏酸、水杨酸、4-甲氧基水杨酸、腺苷、山梨酸组合的体外抗氧化作用，并以金氏公式计算q值为指标，研究组合物的协同抗氧化作用。结果表明，在3种抗氧化模型中，水杨酸、4-甲氧基水杨酸、腺苷、山梨酸分别与麦角硫因的组合表现出单纯加和作用；没食子酸、阿魏酸分别与麦角硫因的组合在DPPH自由基和ABTS+自由基清除能力模型中表现出加和作用，在铁离子还原能力模型中表现出协同抗氧化作用，q值分别为1.76和1.51；麦角硫因与绿原酸的组合均表现出协同抗氧化作用，q值分别为1.16、1.17和1.73，为最具潜力的协同抗氧化组合。
Abstract：DPPH radical clearance, ABTS radical clearance, ferric ion reducing antioxidant power(FRAP) were used to evaluate the antioxidant activity of ergothioneine combined with chlorogenic acid, gallic acid, ferulic acid, salicylic acid,4-methoxylsalicylic acid, adenosine or sorbic acid. And the q value of Jin's formula was used to analyze whether they had synergistic effects on antioxidant activity. The results demonstrated that the combinations of salicylic acid, 4-methoxysalicylic acid, adenosine, or sorbic acid with ergothioneine exhibited a simple additive effect in the 3 antioxidant models. Additionally,the combinations of gallic acid with ergothioneine or ferulic acid with ergothione showed a simple additive effect in the DPPH and ABTS+ free radical scavenging capacity models, while demonstrating a synergistic antioxidant effect in the iron ion reducing capacity models. The q values for 2 complexes were 1.76 and 1.51, respectively. Furthermore, the combination of ergothioneine and chlorogenic acid displayed a synergistic antioxidant effect in the 3 antioxidant models, with q values of 1.16,1.17 and 1.73, respectively. The combination of ergothioneine and chlorogenic acid proved to be the most potent synergistic antioxidant combination.
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基本信息:
DOI：10.20099/j.issn.1000-4475.2024.0043
中图分类号:TQ658
引用信息:
[1]黄政皖,唐毓萍,彭振刚.麦角硫因与7种抗氧化剂组合的抗氧化作用[J].香料香精化妆品,2025,No.208(01):109-114.DOI:10.20099/j.issn.1000-4475.2024.0043.